Nutrition Notes Selisseo (Hydroxy-Selenomethionine): Effects on the Immune System in Swine Facebook Twitter LinkedIn Michael Edmonds, Ph.D., Vice President, Swine and Poultry Nutrition Developing feeding strategies to help reduce the negative effects of stress on swine is an ongoing challenge. Stressful conditions can increase what are called reactive oxygen species (ROS) which can damage cells and impair immune system function. These ROS are activated molecules of oxygen which increase during late pregnancy and lactation in sows, and during weaning and environmental changes in young pigs. One way to help protect cells from ROS damage is by enhancing the pigs’ antioxidant defense system. One of the key nutrients in this process is selenium. Selenium is stored in tissues as selenium-containing proteins. Research shows that the use of hydroxy-selenomethinine, commercially known as Selisseo, results in significantly higher amounts of selenium deposited into muscle compared to selenium yeast or sodium selenite. Thus, when the pig is stressed, the enhanced selenium reserves in tissues are available to help with the immune response. Summary Based on extensive research studies with Selisseo, the incorporation of Selisseo as a standard in the Kent Sow and Starter programs will provide additional support for immune system function. Download Entire Document Related Nutrition Notes Effect of NutriVantage® and/or Chromax in Grow-Finish Pigs Developing products and feed programs to help producers raise pork more efficiently to feed a growing population is an ongoing effort at the Kent Research Farm. NutriVantage® Nutrition Optimizer® for… Read More Supplemental Chromium Sources in Grown-Finish Pigs Developing products and feed programs, to help producers raise pork more efficiently, is an ongoing effort at the Kent Research Farm. Chromium is a trace mineral that helps with the… Read More Amino Acid Imbalance with Excess Methionine in Late-Finishing Pigs: Effects on Performance and Carcass Quality The outbreak of the Covid-19 Pandemic in the spring of 2020, resulted in the shutdown of numerous pork harvest facilities across the country. This resulted in many complications in the… Read More Want to learn more from KNG research? Give us your email address to be notified when we publish new Nutrition Notes articles.